Michael R Lieber Selected Research

AICDA (activation-induced cytidine deaminase)

1/2022	The mechanisms of human lymphoid chromosomal translocations and their medical relevance.
1/2021	Mechanistic basis for chromosomal translocations at the E2A gene and its broader relevance to human B cell malignancies.
1/2016	Mechanisms of human lymphoid chromosomal translocations.

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Michael R Lieber Research Topics

Disease

14	Neoplasms (Cancer) 01/2021 - 06/2004
11	Genetic Translocation (Chromosomal Translocation) 01/2022 - 03/2004
6	Chromosome Breakage 01/2020 - 03/2002
4	Lymphoma (Lymphomas) 01/2016 - 03/2009
4	Genomic Instability 03/2010 - 03/2002
3	Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome) 01/2020 - 03/2002
2	Severe combined immunodeficiency with sensitivity to ionizing radiation 01/2022 - 03/2002
2	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2021 - 07/2015
2	Leukemia 01/2016 - 09/2009
1	Hematologic Neoplasms (Hematological Malignancy) 01/2021
1	Poisoning 11/2019
1	Neuroblastoma 01/2016
1	Breast Neoplasms (Breast Cancer) 01/2016
1	Chromosomal Instability (Chromosome Stability) 01/2016
1	B-Cell Lymphoma (Lymphoma, B Cell) 05/2013
1	Blast Crisis (Blast Phase) 09/2009
1	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 09/2009
1	Chromosome Fragility 03/2009
1	Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular) 09/2006
1	Microcephaly 01/2006
1	Premature Aging 06/2004
1	Lymphoid Leukemia 11/2002
1	Hypersensitivity (Allergy) 03/2002

Drug/Important Bio-Agent (IBA)

17	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 03/2002
5	B-Form DNA (B-DNA)IBA 06/2007 - 06/2004
4	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2019 - 03/2002
4	EnzymesIBA 01/2010 - 03/2002
3	AICDA (activation-induced cytidine deaminase)IBA 01/2022 - 01/2016
3	Proteins (Proteins, Gene)FDA Link 01/2021 - 03/2002
2	lysyl- arginyl- alanyl- lysyl- alanyl- lysyl- threonyl- threonyl- lysyl- lysyl- arginine (PKCS)IBA 01/2022 - 01/2020
2	Biological ProductsIBA 01/2017 - 03/2004
2	DNA-Directed RNA Polymerases (RNA Polymerase)IBA 02/2016 - 01/2016
2	DNA Ligase ATPIBA 01/2016 - 01/2006
2	Superoxide Dismutase-1IBA 03/2003 - 03/2002
1	Transcription Factors (Transcription Factor)IBA 01/2021
1	ChromatinIBA 01/2021
1	Pharmaceutical PreparationsIBA 01/2021
1	Biomarkers (Surrogate Marker)IBA 12/2016
1	Single-Stranded DNA (DNA, Single Stranded)IBA 02/2016
1	1,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA 01/2016
1	DNA Ligases (Ligases, DNA)IBA 01/2016
1	A-Form DNA (A-DNA)IBA 01/2016
1	CytokinesIBA 07/2015
1	Histones (Histone)IBA 09/2014
1	Immunoglobulin Heavy Chains (Immunoglobulin Heavy Chain)IBA 05/2013
1	Nucleic Acid Heteroduplexes (Heteroduplex DNA)IBA 03/2010
1	PurinesIBA 03/2010
1	Antigen Receptors (Antigen Receptor)IBA 01/2010
1	Imatinib Mesylate (Gleevec)FDA Link 09/2009
1	histone H3 trimethyl Lys4IBA 06/2009
1	hydrogen sulfite (bisulfite)IBA 03/2009
1	Insulin-Like Growth Factor I (IGF-1)IBA 11/2008
1	Ligases (Synthetase)IBA 01/2008
1	Immunoglobulins (Immunoglobulin)IBA 08/2005
1	Nuclear Proteins (Protein, Nuclear)IBA 06/2004
1	Tumor Suppressor Protein p14ARF (p14ARF)IBA 11/2002
1	Protein Sorting Signals (Signal Peptide)IBA 11/2002
1	Oxygen (Dioxygen)IBA 03/2002
1	AntioxidantsIBA 03/2002

Therapy/Procedure

1	Therapeutics 01/2020
1	Ligation 01/2017